Version 5.4
Homo sapiens Gene: APOL2
Summary
InnateDB Gene IDBG-5722.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol APOL2
Gene Name apolipoprotein L, 2
Synonyms APOL-II; APOL3
Species Homo sapiens
Ensembl Gene ENSG00000128335
Encoded Proteins
IDBP-5724
apolipoprotein L, 2
IDBP-72824
apolipoprotein L, 2
IDBP-374522
apolipoprotein L, 2
IDBP-374524
apolipoprotein L, 2
IDBP-584080
apolipoprotein L, 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a member of the apolipoprotein L gene family. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids or allow the binding of lipids to organelles. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:36226203-36239954
Strand Reverse strand
Band q12.3
Transcripts
ENST00000249066 ENSP00000249066
ENST00000358502 ENSP00000351292
ENST00000451256 ENSP00000403153
ENST00000454728 ENSP00000400486
ENST00000476579
ENST00000489186
ENST00000473549
ENST00000484830
ENST00000529194 ENSP00000431231
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0008035 high-density lipoprotein particle binding
GO:0008289 lipid binding
Biological Process
GO:0006629 lipid metabolic process
GO:0006869 lipid transport
GO:0006953 acute-phase response
GO:0007275 multicellular organismal development
GO:0008203 cholesterol metabolic process
GO:0042157 lipoprotein metabolic process
GO:0060135 maternal process involved in female pregnancy
Cellular Component
GO:0005576 extracellular region
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000056656
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.474740
RefSeq NM_030882 NM_145637
HUGO
OMIM
CCDS CCDS43014
HPRD 06263
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca