Version 5.4
Homo sapiens Gene: INO80B
Summary
InnateDB Gene IDBG-57388.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol INO80B
Gene Name INO80 complex subunit B
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000115274
Encoded Proteins
IDBP-57390
INO80 complex subunit B
IDBP-295499
INO80 complex subunit B
IDBP-295498
INO80 complex subunit B
IDBP-380669
INO80 complex subunit B
IDBP-380672
INO80 complex subunit B
IDBP-380674
INO80 complex subunit B
IDBP-380677
INO80 complex subunit B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a subunit of an ATP-dependent chromatin remodeling complex, INO80, which plays a role in DNA and nucleosome-activated ATPase activity and ATP-dependent nucleosome sliding. Readthrough transcription of this gene into the neighboring downstream gene, which encodes WW domain-binding protein 1, generates a non-coding transcript. [provided by RefSeq, Feb 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:74455023-74457960
Strand Forward strand
Band p13.1
Transcripts
ENST00000233331 ENSP00000233331
ENST00000409917 ENSP00000387267
ENST00000409493 ENSP00000386937
ENST00000431187 ENSP00000389887
ENST00000452361 ENSP00000388677
ENST00000441673 ENSP00000392498
ENST00000455562 ENSP00000398740
ENST00000494986
ENST00000471577
ENST00000473618
ENST00000469849
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 23 [view]
Protein-Protein 21 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0031011 Ino80 complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000030034
View Gene Order
ENSBTAG00000001840
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.410786
RefSeq NM_031288
HUGO
OMIM
CCDS CCDS1942
HPRD 17110
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca