Homo sapiens Gene: TUBB2A
Summary
InnateDB Gene IDBG-57522.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TUBB2A
Gene Name tubulin, beta 2A class IIa
Synonyms CDCBM5; dJ40E16.7; TUBB; TUBB2;
Species Homo sapiens
Ensembl Gene ENSG00000137267
Encoded Proteins
tubulin, beta 2A class IIa
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 6:3153669-3157526
Strand Reverse strand
Band p25.2
Transcripts
ENST00000333628 ENSP00000369703
ENST00000489942
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 101 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 101 [view]
Protein-Protein 101 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005200 structural constituent of cytoskeleton
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0006457 protein folding
GO:0007017 microtubule-based process
GO:0044267 cellular protein metabolic process
GO:0051084 'de novo' posttranslational protein folding
GO:0051258 protein polymerization
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005874 microtubule
GO:0043234 protein complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Formation of tubulin folding intermediates by CCT/TriC pathway
Protein folding pathway
Post-chaperonin tubulin folding pathway pathway
MHC class II antigen presentation pathway
Transmembrane transport of small molecules pathway
Kinesins pathway
Developmental Biology pathway
Signaling by Hedgehog pathway
Recruitment of NuMA to mitotic centrosomes pathway
Recruitment of mitotic centrosome proteins and complexes pathway
Transport of connexons to the plasma membrane pathway
Axon guidance pathway
Signal Transduction pathway
Separation of Sister Chromatids pathway
Hedgehog 'off' state pathway
Gap junction trafficking pathway
Chaperonin-mediated protein folding pathway
Mitotic Prometaphase pathway
Cell Cycle pathway
Recycling pathway of L1 pathway
Orphan transporters pathway
Metabolism of proteins pathway
Adaptive Immune System pathway
Immune System pathway
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding pathway
Gap junction assembly pathway
M Phase pathway
Mitotic Anaphase pathway
Centrosome maturation pathway
G2/M Transition pathway
Translocation of GLUT4 to the plasma membrane pathway
L1CAM interactions pathway
Factors involved in megakaryocyte development and platelet production pathway
Prefoldin mediated transfer of substrate to CCT/TriC pathway
Cell Cycle, Mitotic pathway
Mitotic G2-G2/M phases pathway
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane pathway
Resolution of Sister Chromatid Cohesion pathway
Gap junction trafficking and regulation pathway
Hemostasis pathway
Membrane Trafficking pathway
Mitotic Metaphase and Anaphase pathway
KEGG
Phagosome pathway
Gap junction pathway
Pathogenic Escherichia coli infection pathway
INOH
PID BIOCARTA
PID NCI
Signaling events mediated by HDAC Class II
Signaling events mediated by HDAC Class III
Cross-References
SwissProt Q13885
TrEMBL
UniProt Splice Variant
Entrez Gene 7280
UniGene Hs.731930
RefSeq NM_001069
HUGO HGNC:12412
OMIM 615101
CCDS CCDS4484
HPRD 01852
IMGT
EMBL AL031963 AY159127 BC001194 BC018780 CR541958 X79535
GenPept AAH01194 AAH18780 AAN85571 CAA56071 CAD70628 CAG46756
RNA Seq Atlas 7280