Homo sapiens Gene: TUBB2B | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-57587.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | TUBB2B | ||||||||||||||||||||||
Gene Name | tubulin, beta 2B class IIb | ||||||||||||||||||||||
Synonyms | |||||||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||||||
Ensembl Gene | ENSG00000137285 | ||||||||||||||||||||||
Encoded Proteins |
tubulin, beta 2B class IIb
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
The protein encoded by this gene is a beta isoform of tubulin, which binds GTP and is a major component of microtubules. This gene is highly similar to TUBB2A and TUBB2C. Defects in this gene are a cause of asymmetric polymicrogyria. [provided by RefSeq, Mar 2010] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 6:3224261-3231730 | ||||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||||
Band | p25.2 | ||||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 41 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Mus musculus
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Gene ID
Gene Order
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Pathways | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Resolution of Sister Chromatid Cohesion pathway
Mitotic Prometaphase pathway
Separation of Sister Chromatids pathway
Recruitment of NuMA to mitotic centrosomes pathway
Recruitment of mitotic centrosome proteins and complexes pathway
MHC class II antigen presentation pathway
Kinesins pathway
Factors involved in megakaryocyte development and platelet production pathway
Post-chaperonin tubulin folding pathway pathway
Prefoldin mediated transfer of substrate to CCT/TriC pathway
Formation of tubulin folding intermediates by CCT/TriC pathway
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane pathway
Transport of connexons to the plasma membrane pathway
Gap junction assembly pathway
Translocation of GLUT4 to the plasma membrane pathway
Recycling pathway of L1 pathway
L1CAM interactions pathway
Protein folding pathway
Transmembrane transport of small molecules pathway
Developmental Biology pathway
Signaling by Hedgehog pathway
Axon guidance pathway
Signal Transduction pathway
Hedgehog 'off' state pathway
Gap junction trafficking pathway
Chaperonin-mediated protein folding pathway
Cell Cycle pathway
Orphan transporters pathway
Metabolism of proteins pathway
Adaptive Immune System pathway
Immune System pathway
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding pathway
M Phase pathway
Mitotic Anaphase pathway
Centrosome maturation pathway
G2/M Transition pathway
Cell Cycle, Mitotic pathway
Mitotic G2-G2/M phases pathway
Gap junction trafficking and regulation pathway
Hemostasis pathway
Membrane Trafficking pathway
Mitotic Metaphase and Anaphase pathway
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KEGG |
Pathogenic Escherichia coli infection pathway
Gap junction pathway
Phagosome pathway
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INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Cross-References | |||||||||||||||||||||||
SwissProt | Q9BVA1 | ||||||||||||||||||||||
TrEMBL | A0A024QZU2 A1L195 O43209 | ||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | 347733 | ||||||||||||||||||||||
UniGene | Hs.300701 Hs.725581 | ||||||||||||||||||||||
RefSeq | NM_178012 | ||||||||||||||||||||||
HUGO | HGNC:30829 | ||||||||||||||||||||||
OMIM | 612850 | ||||||||||||||||||||||
CCDS | CCDS4485 | ||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
EMBL | AF035316 AK289433 AL445309 BC001352 BC063610 BC127872 BT019930 CH471087 CR456788 | ||||||||||||||||||||||
GenPept | AAB88188 AAH01352 AAH63610 AAI27873 AAV38733 BAF82122 CAG33069 CAI40952 EAW55125 EAW55126 EAW55127 | ||||||||||||||||||||||
RNA Seq Atlas | 347733 | ||||||||||||||||||||||