Version 5.4
Homo sapiens Gene: ACAD10
Summary
InnateDB Gene IDBG-57656.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ACAD10
Gene Name acyl-CoA dehydrogenase family, member 10
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000111271
Encoded Proteins
IDBP-57658
acyl-CoA dehydrogenase family, member 10
IDBP-383420
acyl-CoA dehydrogenase family, member 10
IDBP-485593
acyl-CoA dehydrogenase family, member 10
IDBP-597066
acyl-CoA dehydrogenase family, member 10
IDBP-603457
acyl-CoA dehydrogenase family, member 10
IDBP-595604
acyl-CoA dehydrogenase family, member 10
IDBP-590594
acyl-CoA dehydrogenase family, member 10
IDBP-602273
acyl-CoA dehydrogenase family, member 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the acyl-CoA dehydrogenase family of enzymes (ACADs), which participate in the beta-oxidation of fatty acids in mitochondria. The encoded enzyme contains a hydrolase domain at the N-terminal portion, a serine/threonine protein kinase catlytic domain in the central region, and a conserved ACAD domain at the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Nov 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:111686056-111757107
Strand Forward strand
Band q24.12
Transcripts
ENST00000313698 ENSP00000325137
ENST00000455480 ENSP00000389813
ENST00000413681
ENST00000511915
ENST00000514615 ENSP00000421527
ENST00000509936
ENST00000507135
ENST00000515283 ENSP00000449097
ENST00000502746
ENST00000514847
ENST00000507683 ENSP00000446711
ENST00000503490
ENST00000508303
ENST00000504803
ENST00000505487
ENST00000507688
ENST00000512792
ENST00000549590 ENSP00000446959
ENST00000552965 ENSP00000446998
ENST00000552706 ENSP00000447561
ENST00000552177
ENST00000546647
ENST00000550198
ENST00000547491
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003995 acyl-CoA dehydrogenase activity
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0016787 hydrolase activity
GO:0050660 flavin adenine dinucleotide binding
Biological Process
GO:0008152 metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029456
View Gene Order
ENSBTAG00000001164
Not yet available
Cross-References
SwissProt
TrEMBL F8VXK4
UniProt Splice Variant
Entrez Gene 80724
UniGene Hs.331141 Hs.738338
RefSeq NM_001136538 NM_025247
HUGO HGNC:21597
OMIM 611181
CCDS CCDS31903 CCDS44973
HPRD 10625
IMGT
EMBL AC002996
GenPept
RNA Seq Atlas 80724

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca