Version 5.4
Homo sapiens Gene: FAIM
Summary
InnateDB Gene IDBG-58532.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FAIM
Gene Name Fas apoptotic inhibitory molecule
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000158234
Encoded Proteins
IDBP-58534
Fas apoptotic inhibitory molecule
IDBP-58538
Fas apoptotic inhibitory molecule
IDBP-244449
Fas apoptotic inhibitory molecule
IDBP-244451
Fas apoptotic inhibitory molecule
IDBP-478814
Fas apoptotic inhibitory molecule
IDBP-483624
Fas apoptotic inhibitory molecule
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene protects against death receptor-triggered apoptosis and regulates B-cell signaling and differentiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:138608606-138633376
Strand Forward strand
Band q22.3
Transcripts
ENST00000338446 ENSP00000342805
ENST00000360570 ENSP00000353775
ENST00000393035 ENSP00000376755
ENST00000393034 ENSP00000376754
ENST00000470889
ENST00000491175
ENST00000464668 ENSP00000417642
ENST00000479848 ENSP00000420543
ENST00000464912
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006915 apoptotic process
GO:0043066 negative regulation of apoptotic process
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000032463
View Gene Order
ENSBTAG00000023426
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
trkrpathway
Neurotrophic factor-mediated Trk receptor signaling
Cross-References
SwissProt Q9NVQ4
TrEMBL C9JDZ2
UniProt Splice Variant
Entrez Gene 55179
UniGene Hs.173438 Hs.705623
RefSeq NM_018147 NM_001033030 NM_001033031 NM_001033032
HUGO HGNC:18703
OMIM
CCDS CCDS3103 CCDS33864 CCDS33865
HPRD 16874
IMGT
EMBL AC020890 AK001444 AK125477 BC012478 BQ638715 CR457122
GenPept AAH12478 BAA91695 BAC86174 CAG33403
RNA Seq Atlas 55179

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca