Version 5.4
Homo sapiens Gene: TESC
Summary
InnateDB Gene IDBG-59389.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TESC
Gene Name tescalcin
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000088992
Encoded Proteins
IDBP-59391
tescalcin
IDBP-604357
tescalcin
IDBP-604366
tescalcin
IDBP-604365
tescalcin
IDBP-604367
tescalcin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 12:117038923-117099479
Strand Reverse strand
Band q24.22
Transcripts
ENST00000335209 ENSP00000334785
ENST00000470612 ENSP00000432716
ENST00000462502 ENSP00000432608
ENST00000482176
ENST00000549210 ENSP00000450386
ENST00000535198
ENST00000552139
ENST00000541210 ENSP00000445689
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0004860 protein kinase inhibitor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0019212 phosphatase inhibitor activity
GO:0042803 protein homodimerization activity
Biological Process
GO:0006469 negative regulation of protein kinase activity
GO:0008285 negative regulation of cell proliferation
GO:0008584 male gonad development
GO:0010628 positive regulation of gene expression
GO:0030219 megakaryocyte differentiation
GO:0030854 positive regulation of granulocyte differentiation
GO:0032417 positive regulation of sodium:proton antiporter activity
GO:0033628 regulation of cell adhesion mediated by integrin
GO:0043086 negative regulation of catalytic activity
GO:0045654 positive regulation of megakaryocyte differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0050821 protein stabilization
GO:0051604 protein maturation
GO:0071300 cellular response to retinoic acid
GO:0072661 protein targeting to plasma membrane
Cellular Component
GO:0001726 ruffle
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0030027 lamellipodium
GO:0032587 ruffle membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029359
View Gene Order
ENSBTAG00000044078
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001168325 NM_017899
HUGO
OMIM
CCDS CCDS53835 CCDS9183
HPRD 11649
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca