Version 5.4
Homo sapiens Gene: ARHGAP28
Summary
InnateDB Gene IDBG-594.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARHGAP28
Gene Name Rho GTPase activating protein 28
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000088756
Encoded Proteins
IDBP-596
Rho GTPase activating protein 28
IDBP-598
Rho GTPase activating protein 28
IDBP-600
Rho GTPase activating protein 28
IDBP-362859
Rho GTPase activating protein 28
IDBP-602649
Rho GTPase activating protein 28
IDBP-588909
Rho GTPase activating protein 28
IDBP-598581
Rho GTPase activating protein 28
IDBP-725910
IDBP-727235
IDBP-727957
IDBP-726877
IDBP-725622
IDBP-726663
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 18:6729718-6915716
Strand Forward strand
Band p11.31
Transcripts
ENST00000262227 ENSP00000262227
ENST00000314319 ENSP00000313506
ENST00000383472 ENSP00000372964
ENST00000419673 ENSP00000392660
ENST00000532723 ENSP00000433390
ENST00000531294 ENSP00000437262
ENST00000532996 ENSP00000435990
ENST00000584287 ENSP00000464310
ENST00000584387 ENSP00000462831
ENST00000583410 ENSP00000464141
ENST00000577524 ENSP00000463672
ENST00000581099 ENSP00000462912
ENST00000579689 ENSP00000463143
ENST00000579245
ENST00000579796
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
Biological Process
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0043547 positive regulation of GTPase activity
GO:0051056 regulation of small GTPase mediated signal transduction
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005829 cytosol
GO:0030054 cell junction
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000024043
View Gene Order
ENSBTAG00000019036
Not yet available
Pathways
NETPATH
REACTOME
REACT_11051
Rho GTPase cycle pathway
REACT_11044
Signaling by Rho GTPases pathway
REACT_111102
Signal Transduction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.183114 Hs.618594 Hs.625577 Hs.701154 Hs.738832
RefSeq NM_001010000 XM_005258144 XM_005258145
HUGO
OMIM
CCDS CCDS32785
HPRD 10961
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca