Homo sapiens Gene: SLC9A9
Summary
InnateDB Gene IDBG-59871.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC9A9
Gene Name solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000181804
Encoded Proteins
solute carrier family 9 (sodium/hydrogen exchanger), member 9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a sodium/proton exchanger that is a member of the solute carrier 9 protein family. The encoded protein localizes the to the late recycling endosomes and may play an important role in maintaining cation homeostasis. Mutations in this gene are associated with autism susceptibility 16 and attention-deficit/hyperactivity disorder. [provided by RefSeq, Mar 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:143265222-143848531
Strand Reverse strand
Band q24
Transcripts
ENST00000316549 ENSP00000320246
ENST00000483124
ENST00000474727 ENSP00000419090
ENST00000474151 ENSP00000418627
ENST00000498717
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0015299 solute:proton antiporter activity
GO:0015385 sodium:proton antiporter activity
Biological Process
GO:0006811 ion transport
GO:0006812 cation transport
GO:0006814 sodium ion transport
GO:0006885 regulation of pH
GO:0035725 sodium ion transmembrane transport
GO:0055085 transmembrane transport
GO:1902600 hydrogen ion transmembrane transport
Cellular Component
GO:0016021 integral component of membrane
GO:0031902 late endosome membrane
GO:0055037 recycling endosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Transmembrane transport of small molecules pathway
Sodium/Proton exchangers pathway
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.302257 Hs.629066 Hs.708285
RefSeq NM_173653
HUGO
OMIM
CCDS CCDS33872
HPRD 12226
IMGT
EMBL
GenPept
RNA Seq Atlas