Version 5.4
Homo sapiens Gene: SRP14
Summary
InnateDB Gene IDBG-6032.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SRP14
Gene Name signal recognition particle 14kDa (homologous Alu RNA binding protein)
Synonyms ALURBP
Species Homo sapiens
Ensembl Gene ENSG00000140319
Encoded Proteins
IDBP-6034
signal recognition particle 14kDa (homologous Alu RNA binding protein)
IDBP-599432
signal recognition particle 14kDa (homologous Alu RNA binding protein)
IDBP-586666
signal recognition particle 14kDa (homologous Alu RNA binding protein)
IDBP-594714
signal recognition particle 14kDa (homologous Alu RNA binding protein)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 15:40035739-40039188
Strand Reverse strand
Band q15.1
Transcripts
ENST00000267884 ENSP00000267884
ENST00000558527
ENST00000558720 ENSP00000453361
ENST00000560773 ENSP00000452756
ENST00000559439
ENST00000559475
ENST00000559081 ENSP00000453120
ENST00000558243
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 59 experimentally validated interaction(s) in this database.
Experimentally validated
Total 59 [view]
Protein-Protein 59 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0008312 7S RNA binding
GO:0030942 endoplasmic reticulum signal peptide binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006412 translation
GO:0006613 cotranslational protein targeting to membrane
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
GO:0010467 gene expression
GO:0042493 response to drug
GO:0044267 cellular protein metabolic process
GO:0045047 protein targeting to ER
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005786 signal recognition particle, endoplasmic reticulum targeting
GO:0005829 cytosol
GO:0045171 intercellular bridge
GO:0048500 signal recognition particle
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000009549
View Gene Order
ENSBTAG00000014353
Not yet available
Pathways
NETPATH
REACTOME
REACT_115902
SRP-dependent cotranslational protein targeting to membrane pathway
REACT_1014
Translation pathway
REACT_17015
Metabolism of proteins pathway
REACT_71
Gene Expression pathway
KEGG
hsa03060
Protein export pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.661971
RefSeq NM_003134
HUGO
OMIM
CCDS CCDS42017
HPRD 02831
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca