Homo sapiens Gene: IFT27
Summary
InnateDB Gene IDBG-6045.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IFT27
Gene Name intraflagellar transport 27 homolog (Chlamydomonas)
Synonyms BBS19; RABL4; RAYL;
Species Homo sapiens
Ensembl Gene ENSG00000100360
Encoded Proteins
intraflagellar transport 27 homolog (Chlamydomonas)
intraflagellar transport 27 homolog (Chlamydomonas)
intraflagellar transport 27 homolog (Chlamydomonas)
intraflagellar transport 27 homolog (Chlamydomonas)
intraflagellar transport 27 homolog (Chlamydomonas)
intraflagellar transport 27 homolog (Chlamydomonas)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a GTP-binding protein that is a core component of the intraflagellar transport complex B. Characterization of the similar Chlamydomonas protein indicates a function in cell cycle control. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:36758202-36776256
Strand Reverse strand
Band q12.3
Transcripts
ENST00000340630 ENSP00000343593
ENST00000433985 ENSP00000393541
ENST00000415653 ENSP00000404556
ENST00000417951 ENSP00000392016
ENST00000430701 ENSP00000390016
ENST00000440696 ENSP00000399606
ENST00000495987
ENST00000474616
ENST00000495555
ENST00000471809
ENST00000465023
ENST00000476548
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
Cellular Component
GO:0005622 intracellular
GO:0005813 centrosome
GO:0005929 cilium
GO:0016020 membrane
GO:0030992 intraciliary transport particle B
GO:0031514 motile cilium
GO:0097225 sperm midpiece
GO:0097228 sperm principal piece
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL B1AH56 B1AH58
UniProt Splice Variant
Entrez Gene 11020
UniGene Hs.415172 Hs.735977
RefSeq NM_001177701 NM_006860 XM_006724106
HUGO HGNC:18626
OMIM 615870
CCDS CCDS13932 CCDS54523
HPRD
IMGT
EMBL Z80897
GenPept
RNA Seq Atlas 11020