Version 5.4
Homo sapiens Gene: IFT27
Summary
InnateDB Gene IDBG-6045.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IFT27
Gene Name intraflagellar transport 27 homolog (Chlamydomonas)
Synonyms BBS19; RABL4; RAYL
Species Homo sapiens
Ensembl Gene ENSG00000100360
Encoded Proteins
IDBP-6049
intraflagellar transport 27 homolog (Chlamydomonas)
IDBP-374909
intraflagellar transport 27 homolog (Chlamydomonas)
IDBP-374916
intraflagellar transport 27 homolog (Chlamydomonas)
IDBP-374918
intraflagellar transport 27 homolog (Chlamydomonas)
IDBP-374919
intraflagellar transport 27 homolog (Chlamydomonas)
IDBP-374920
intraflagellar transport 27 homolog (Chlamydomonas)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a GTP-binding protein that is a core component of the intraflagellar transport complex B. Characterization of the similar Chlamydomonas protein indicates a function in cell cycle control. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:36758202-36776256
Strand Reverse strand
Band q12.3
Transcripts
ENST00000340630 ENSP00000343593
ENST00000433985 ENSP00000393541
ENST00000415653 ENSP00000404556
ENST00000417951 ENSP00000392016
ENST00000430701 ENSP00000390016
ENST00000440696 ENSP00000399606
ENST00000495987
ENST00000474616
ENST00000495555
ENST00000471809
ENST00000465023
ENST00000476548
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
Cellular Component
GO:0005622 intracellular
GO:0005813 centrosome
GO:0005929 cilium
GO:0016020 membrane
GO:0030992 intraciliary transport particle B
GO:0031514 motile cilium
GO:0097225 sperm midpiece
GO:0097228 sperm principal piece
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000016637
View Gene Order
ENSBTAG00000026657
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.415172 Hs.735977
RefSeq NM_001177701 NM_006860 XM_006724106
HUGO
OMIM
CCDS CCDS13932 CCDS54523
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca