Version 5.4
Homo sapiens Gene: TRIAP1
Summary
InnateDB Gene IDBG-60567.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRIAP1
Gene Name TP53 regulated inhibitor of apoptosis 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000170855
Encoded Proteins
IDBP-589355
TP53 regulated inhibitor of apoptosis 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 12:120443961-120446412
Strand Reverse strand
Band q24.31
Transcripts
ENST00000302432
ENST00000546954 ENSP00000449795
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0002039 p53 binding
GO:0005515 protein binding
GO:1990050 phosphatidic acid transporter activity
Biological Process
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0015914 phospholipid transport
GO:0030330 DNA damage response, signal transduction by p53 class mediator
GO:0034644 cellular response to UV
GO:0043066 negative regulation of apoptotic process
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0090201 negative regulation of release of cytochrome c from mitochondria
GO:0097035 regulation of membrane lipid distribution
GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:2001140 positive regulation of phospholipid transport
Cellular Component
GO:0005739 mitochondrion
GO:0005758 mitochondrial intermembrane space
GO:0043234 protein complex
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029535
View Gene Order
ENSBTAG00000012790
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
p53downstreampathway
Direct p53 effectors
Cross-References
SwissProt O43715
TrEMBL
UniProt Splice Variant
Entrez Gene 51499
UniGene
RefSeq NM_016399
HUGO HGNC:26937
OMIM 614943
CCDS CCDS9198
HPRD 13698
IMGT
EMBL AF161481 AK312006 AL021546 BC002638 BC055313 CH471054 U75688
GenPept AAF29096 AAH02638 AAH55313 AAR00584 BAG34944 CAA16495 EAW98192
RNA Seq Atlas 51499

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca