InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: RNF10

Summary

InnateDB Gene

IDBG-60736.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RNF10

Gene Name

ring finger protein 10

Synonyms

RIE2

Species

Homo sapiens

Ensembl Gene

ENSG00000022840

Encoded Proteins

IDBP-60738

ring finger protein 10

IDBP-384206

ring finger protein 10

IDBP-596364

ring finger protein 10

IDBP-586396

ring finger protein 10

IDBP-597677

ring finger protein 10

IDBP-596165

ring finger protein 10

IDBP-598243

ring finger protein 10

IDBP-587260

ring finger protein 10

IDBP-595267

ring finger protein 10

IDBP-591020

ring finger protein 10

IDBP-599394

ring finger protein 10

IDBP-589850

ring finger protein 10

IDBP-598094

ring finger protein 10

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

The protein encoded by this gene contains a ring finger motif, which is known to be involved in protein-protein interactions. The specific function of this protein has not yet been determined. EST data suggests the existence of multiple alternatively spliced transcript variants, however, their full length nature is not known. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 12:120533480-120577594

Strand

Forward strand

Band

q24.31

Transcripts

ENST00000325954	ENSP00000322242
ENST00000366112
ENST00000413266	ENSP00000415682
ENST00000539486	ENSP00000438638
ENST00000542438	ENSP00000444770
ENST00000538796	ENSP00000443000
ENST00000551139
ENST00000536869	ENSP00000443790
ENST00000537997	ENSP00000443235
ENST00000543578
ENST00000535417
ENST00000542207	ENSP00000439510
ENST00000543675
ENST00000537740	ENSP00000437392
ENST00000537376
ENST00000546262	ENSP00000439221
ENST00000544124
ENST00000540046	ENSP00000439859
ENST00000545419	ENSP00000445160
ENST00000535395
ENST00000535470
ENST00000538254	ENSP00000441487
ENST00000543757
ENST00000542701
ENST00000544805

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 34 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	34 [view]
Protein-Protein	33 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0044212	transcription regulatory region DNA binding
GO:0046872	metal ion binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0010626	negative regulation of Schwann cell proliferation
GO:0031643	positive regulation of myelination
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0051865	protein autoubiquitination

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm

Orthologs

Species

Mus musculus

Bos taurus

Gene ID

Gene Order

ENSMUSG00000041740

View Gene Order

ENSBTAG00000015767

Not yet available

Cross-References

SwissProt

Q8N5U6

TrEMBL

A0A024RBP0 F5H3A4 F5H510 F5H5P6 F5H5Z1 H0YFQ9 H0YG28 H0YGL7 H0YGX5

UniProt Splice Variant

Entrez Gene

9921

UniGene

Hs.442798 Hs.619394 Hs.630749

RefSeq

NM_014868 XM_006719717

HUGO

HGNC:10055

OMIM

CCDS

CCDS9201

HPRD

IMGT

EMBL

AB027196 AC063943 AL389976 BC016622 BC031596 BC101709 BC101715 BT006974 CH471054 D87451

GenPept

AAH16622 AAH31596 AAI01710 AAI01716 AAP35620 BAA13392 BAA84708 CAB97533 EAW98200 EAW98203 EAW98204

RNA Seq Atlas

9921