Version 5.4
Homo sapiens Gene: SERP1
Summary
InnateDB Gene IDBG-61176.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SERP1
Gene Name stress-associated endoplasmic reticulum protein 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000120742
Encoded Proteins
IDBP-61178
stress-associated endoplasmic reticulum protein 1
IDBP-484074
stress-associated endoplasmic reticulum protein 1
IDBP-480026
stress-associated endoplasmic reticulum protein 1
IDBP-474855
stress-associated endoplasmic reticulum protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:150541994-150603228
Strand Reverse strand
Band q25.1
Transcripts
ENST00000239944 ENSP00000239944
ENST00000479209 ENSP00000420076
ENST00000487153 ENSP00000420002
ENST00000491660 ENSP00000419472
ENST00000491195
ENST00000490945
ENST00000463647
ENST00000484608
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
Experimentally validated
Total 16 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0001501 skeletal system development
GO:0006006 glucose metabolic process
GO:0006464 cellular protein modification process
GO:0006486 protein glycosylation
GO:0006950 response to stress
GO:0006987 activation of signaling protein activity involved in unfolded protein response
GO:0007009 plasma membrane organization
GO:0009791 post-embryonic development
GO:0010259 multicellular organismal aging
GO:0015031 protein transport
GO:0030968 endoplasmic reticulum unfolded protein response
GO:0032024 positive regulation of insulin secretion
GO:0044267 cellular protein metabolic process
GO:0045727 positive regulation of translation
GO:0046622 positive regulation of organ growth
GO:0048644 muscle organ morphogenesis
GO:0060124 positive regulation of growth hormone secretion
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005840 ribosome
GO:0005881 cytoplasmic microtubule
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000027808
View Gene Order
ENSBTAG00000009104
Not yet available
Pathways
NETPATH
REACTOME
REACT_18273
XBP1(S) activates chaperone genes pathway
REACT_18368
IRE1alpha activates chaperones pathway
REACT_18356
Unfolded Protein Response (UPR) pathway
REACT_17015
Metabolism of proteins pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL C9JUH5
UniProt Splice Variant
Entrez Gene 27230
UniGene Hs.518326 Hs.595505 Hs.602644 Hs.713956
RefSeq NM_014445
HUGO HGNC:10759
OMIM
CCDS CCDS3150
HPRD 18037
IMGT
EMBL AC069236 AC107426
GenPept
RNA Seq Atlas 101928061 27230

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca