Version 5.4
Homo sapiens Gene: MTL5
Summary
InnateDB Gene IDBG-61529.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MTL5
Gene Name metallothionein-like 5, testis-specific (tesmin)
Synonyms CXCDC2; MTLT; TESMIN
Species Homo sapiens
Ensembl Gene ENSG00000132749
Encoded Proteins
IDBP-61531
metallothionein-like 5, testis-specific (tesmin)
IDBP-379814
metallothionein-like 5, testis-specific (tesmin)
IDBP-719063
IDBP-592330
metallothionein-like 5, testis-specific (tesmin)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Metallothionein proteins are highly conserved low-molecular-weight cysteine-rich proteins that are induced by and bind to heavy metal ions and have no enzymatic activity. They may play a central role in the regulation of cell growth and differentiation and are involved in spermatogenesis. This gene encodes a metallothionein-like protein which has been shown to be expressed differentially in mouse testis and ovary. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:68707440-68751564
Strand Reverse strand
Band q13.3
Transcripts
ENST00000255087 ENSP00000255087
ENST00000443940 ENSP00000403086
ENST00000432435
ENST00000438124
ENST00000544398
ENST00000543240 ENSP00000454311
ENST00000540869
ENST00000544963 ENSP00000440968
ENST00000538944
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0046872 metal ion binding
Biological Process
GO:0006875 cellular metal ion homeostasis
GO:0006952 defense response
GO:0007275 multicellular organismal development
GO:0007283 spermatogenesis
GO:0010038 response to metal ion
GO:0030154 cell differentiation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000024905
View Gene Order
Cross-References
SwissProt Q9Y4I5
TrEMBL
UniProt Splice Variant
Entrez Gene 9633
UniGene Hs.602521 Hs.733722
RefSeq NM_001039656 NM_004923
HUGO HGNC:7446
OMIM 604374
CCDS CCDS44661 CCDS8184
HPRD 09186
IMGT
EMBL AK074817 AK292358 BC027593 BC064579 CH471076 U86074
GenPept AAD24668 AAH27593 AAH64579 BAC11228 BAF85047 EAW74719
RNA Seq Atlas 9633

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca