Version 5.4
Homo sapiens Gene: DHX40
Summary
InnateDB Gene IDBG-61717.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DHX40
Gene Name DEAH (Asp-Glu-Ala-His) box polypeptide 40
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000108406
Encoded Proteins
IDBP-61719
DEAH (Asp-Glu-Ala-His) box polypeptide 40
IDBP-382493
DEAH (Asp-Glu-Ala-His) box polypeptide 40
IDBP-603406
DEAH (Asp-Glu-Ala-His) box polypeptide 40
IDBP-761242
IDBP-762701
IDBP-764070
IDBP-759452
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the DExH/D box family of ATP-dependent RNA helicases that have an essential role in RNA metabolism. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 17.[provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:59565525-59608345
Strand Forward strand
Band q23.1
Transcripts
ENST00000251241 ENSP00000251241
ENST00000425628 ENSP00000388749
ENST00000538926 ENSP00000437958
ENST00000580030 ENSP00000462686
ENST00000577596 ENSP00000462246
ENST00000584385 ENSP00000463025
ENST00000583439
ENST00000578204
ENST00000577549
ENST00000580218 ENSP00000462702
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0008026 ATP-dependent helicase activity
Biological Process
GO:0006200 ATP catabolic process
GO:0006810 transport
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000018425
View Gene Order
ENSBTAG00000017868
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001166301 NM_024612 XM_003846599
HUGO
OMIM
CCDS CCDS11617 CCDS54150
HPRD 06346
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca