Version 5.4
Homo sapiens Gene: RUSC2
Summary
InnateDB Gene IDBG-62526.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RUSC2
Gene Name RUN and SH3 domain containing 2
Synonyms Iporin
Species Homo sapiens
Ensembl Gene ENSG00000198853
Encoded Proteins
IDBP-62528
RUN and SH3 domain containing 2
IDBP-368375
RUN and SH3 domain containing 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a RUN and SH3 domain containing protein that interacts with Rab1b and Rab1-binding protein GM130. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jun 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:35490127-35561898
Strand Forward strand
Band p13.3
Transcripts
ENST00000361226 ENSP00000355177
ENST00000455600 ENSP00000393922
ENST00000468041
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0017137 Rab GTPase binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005829 cytosol
GO:0031410 cytoplasmic vesicle
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000035969
View Gene Order
ENSBTAG00000011403
Not yet available
Cross-References
SwissProt Q8N2Y8
TrEMBL
UniProt Splice Variant
Entrez Gene 9853
UniGene Hs.493796
RefSeq NM_014806 NM_001135999 XM_006716896
HUGO HGNC:23625
OMIM 611053
CCDS CCDS35008
HPRD 18009
IMGT
EMBL AB002373 AL133476 BC029647 BC064843 BC082245 BC132766 BC132770 BC146654 BC150262 CH471071
GenPept AAH29647 AAH64843 AAH82245 AAI32767 AAI32771 AAI46655 AAI50263 BAA20830 CAH70650 EAW58377
RNA Seq Atlas 9853

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca