Version 5.4
Homo sapiens Gene: DKKL1
Summary
InnateDB Gene IDBG-62588.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DKKL1
Gene Name dickkopf-like 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000104901
Encoded Proteins
IDBP-62590
dickkopf-like 1
IDBP-766240
IDBP-762705
IDBP-760232
IDBP-762184
IDBP-765082
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The dickkopf protein family interacts with the Wnt signaling pathway and its members are characterized by two conserved cysteine-rich domains. This gene encodes a secreted protein that has low sequence similarity to the dickkopf-3 protein. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:49361783-49375116
Strand Forward strand
Band q13.33
Transcripts
ENST00000221498 ENSP00000221498
ENST00000596402 ENSP00000470676
ENST00000598682 ENSP00000471812
ENST00000594268 ENSP00000469865
ENST00000597546 ENSP00000472056
ENST00000597873 ENSP00000472866
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
GO:0009653 anatomical structure morphogenesis
GO:0045600 positive regulation of fat cell differentiation
Cellular Component
GO:0005615 extracellular space
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000030792
View Gene Order
ENSBTAG00000012186
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.515855
RefSeq NM_001197301 NM_001197302 NM_014419 XM_006723142 XM_006723143 XM_006723144 XM_006723145
HUGO
OMIM
CCDS CCDS12762
HPRD 10396
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca