InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: MTNR1A

Summary

InnateDB Gene

IDBG-628597.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MTNR1A

Gene Name

Uncharacterized protein

Synonyms

Mel-1A-R

Species

Bos taurus

Ensembl Gene

ENSBTAG00000046938

Encoded Proteins

IDBP-679964

Melatonin receptor 1A

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000168412:
This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 27:15439639-15462319

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000065508

ENSBTAP00000054673

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.

Predicted by orthology
Total	21 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004871	signal transducer activity
GO:0004930	G-protein coupled receptor activity
GO:0005515	protein binding
GO:0008502	melatonin receptor activity
GO:0042562	hormone binding
GO:0097159	organic cyclic compound binding