Version 5.4
Homo sapiens Gene: TRIM7
Summary
InnateDB Gene IDBG-62871.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRIM7
Gene Name tripartite motif containing 7
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000146054
Encoded Proteins
IDBP-62873
tripartite motif containing 7
IDBP-62877
tripartite motif containing 7
IDBP-243855
tripartite motif containing 7
IDBP-243857
tripartite motif containing 7
IDBP-382843
tripartite motif containing 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 23438823
TRIM7 was identified in a systematic screen for positive regulators of innate immune responses.
Entrez Gene
Summary The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1, a B-box type 2, and a coiled-coil region. The protein localizes to both the nucleus and the cytoplasm, and may represent a participant in the initiation of glycogen synthesis. Multiple transcript variants have been found for this gene, and some of them encode the same isoform. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:181193924-181205293
Strand Reverse strand
Band q35.3
Transcripts
ENST00000274773 ENSP00000274773
ENST00000334421 ENSP00000334666
ENST00000393319 ENSP00000376994
ENST00000393315 ENSP00000376991
ENST00000422067 ENSP00000391458
ENST00000504241
ENST00000509199
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000040350
View Gene Order
ENSBTAG00000020954
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.487412 Hs.641172
RefSeq NM_033342 NM_203293 NM_203294 NM_203295 NM_203296 NM_203297
HUGO
OMIM
CCDS CCDS43414 CCDS4462 CCDS4463 CCDS4464
HPRD 11648
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca