Version 5.4
Bos taurus Gene: RP1L1
Summary
InnateDB Gene IDBG-629476.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RP1L1
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000020155
Encoded Proteins
IDBP-680877
retinitis pigmentosa 1-like 1
IDBP-680879
retinitis pigmentosa 1-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000183638:
This gene encodes a member of the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, and two C-terminal large repetitive regions, both of which contain a high percentage of glutamine and glutamic acid residues. This protein is a retinal-specific protein. Its exact length varies among individuals due to the presence of a 16aa repeat in the first C-terminal repetitive region. The 16aa repeat is encoded by the highly polymorphic 48-bp repeat, and 1-6 copies of the 16aa repeat have been identified in normal individuals. The current reference sequence shown here has a single copy of the 16aa repeat. This protein and the RP1 protein, another retinal-specific protein, play essential and synergistic roles in affecting photosensitivity and outer segment morphogenesis of rod photoreceptors. Mutations in this gene cause occult macular dystrophy (OMD). [provided by RefSeq, Sep 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:8508960-8518765
Strand Forward strand
Band
Transcripts
ENSBTAT00000026846 ENSBTAP00000026846
ENSBTAT00000064867 ENSBTAP00000054813
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0035556 intracellular signal transduction
GO:0042461 photoreceptor cell development
GO:0045494 photoreceptor cell maintenance
Cellular Component
GO:0001750 photoreceptor outer segment
GO:0005930 axoneme
GO:0032391 photoreceptor connecting cilium
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000183638
View Gene Order
ENSMUSG00000046049
View Gene Order
Cross-References
SwissProt
TrEMBL G3MZ22
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq
HUGO HGNC:15946
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02021941 DAAA02021942
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca