Bos taurus Gene: MSRA
Summary
InnateDB Gene IDBG-629499.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MSRA
Gene Name Mitochondrial peptide methionine sulfoxide reductase
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000021632
Encoded Proteins
Mitochondrial peptide methionine sulfoxide reductase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000175806:
This protein is ubiquitous and highly conserved. It carries out the enzymatic reduction of methionine sulfoxide to methionine. Human and animal studies have shown the highest levels of expression in kidney and nervous tissue. Its proposed function is the repair of oxidative damage to proteins to restore biological activity. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
This gene encodes a ubiquitous and highly conserved protein that carries out the enzymatic reduction of methionine sulfoxide to methionine. Human and animal studies have shown the highest levels of expression in kidney and nervous tissue. The protein functions in the repair of oxidatively damaged proteins to restore biological activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:8635550-9019576
Strand Reverse strand
Band
Transcripts
ENSBTAT00000028825 ENSBTAP00000028825
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008113 peptide-methionine (S)-S-oxide reductase activity
GO:0016491 oxidoreductase activity
GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
Biological Process
GO:0006979 response to oxidative stress
GO:0030091 protein repair
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Cross-References
SwissProt P54149
TrEMBL
UniProt Splice Variant
Entrez Gene 281312
UniGene Bt.4655 Bt.67939
RefSeq NM_174114
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102980 BT021044 U37150
GenPept AAC48539 AAI02981 AAX09061
RNA Seq Atlas 281312