Version 5.4
Homo sapiens Gene: SLC38A5
Summary
InnateDB Gene IDBG-63007.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC38A5
Gene Name solute carrier family 38, member 5
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000017483
Encoded Proteins
IDBP-370088
solute carrier family 38, member 5
IDBP-370094
solute carrier family 38, member 5
IDBP-370099
solute carrier family 38, member 5
IDBP-370103
solute carrier family 38, member 5
IDBP-370106
solute carrier family 38, member 5
IDBP-813525
solute carrier family 38, member 5
IDBP-813531
solute carrier family 38, member 5
IDBP-813522
solute carrier family 38, member 5
IDBP-813523
solute carrier family 38, member 5
IDBP-813533
solute carrier family 38, member 5
IDBP-813536
solute carrier family 38, member 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a system N sodium-coupled amino acid transporter involved in the transfer of glutamine, asparagine, histidine, serine, alanine, and glycine. The encoded protein does not transport charged amino acids, imino acids, or N-alkylated amino acids. This transporter is not inhibited by lithium.[provided by RefSeq, Jun 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:48458537-48470256
Strand Reverse strand
Band p11.23
Transcripts
ENST00000440085 ENSP00000402988
ENST00000441948 ENSP00000407258
ENST00000413668 ENSP00000403976
ENST00000416711 ENSP00000389644
ENST00000429543 ENSP00000416948
ENST00000497336
ENST00000480105
ENST00000494034 ENSP00000482638
ENST00000488083 ENSP00000483716
ENST00000595796 ENSP00000471683
ENST00000619100 ENSP00000478807
ENST00000615300
ENST00000620913 ENSP00000481291
ENST00000622196 ENSP00000484236
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0015171 amino acid transmembrane transporter activity
GO:0015175 neutral amino acid transmembrane transporter activity
GO:0015187 glycine transmembrane transporter activity
Biological Process
GO:0003333 amino acid transmembrane transport
GO:0006811 ion transport
GO:0006865 amino acid transport
GO:0015804 neutral amino acid transport
GO:0015816 glycine transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031170
View Gene Order
ENSBTAG00000011854
Not yet available
Pathways
NETPATH
REACTOME
REACT_13796
Amino acid transport across the plasma membrane pathway
REACT_19397
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_033518 XM_005272695
HUGO
OMIM
CCDS CCDS14293
HPRD 06718
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca