Version 5.4
Bos taurus Gene: JPH3
Summary
InnateDB Gene IDBG-630253.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol JPH3
Gene Name junctophilin-3
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000006899
Encoded Proteins
IDBP-681704
junctophilin 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000154118:
Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. CAG/CTG repeat expansions at the Huntington's disease (HD)-like 2 locus have been identified in this gene, which is a member of the junctophilin gene family. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:13186023-13260798
Strand Forward strand
Band
Transcripts
ENSBTAT00000009056 ENSBTAP00000009056
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0015278 calcium-release channel activity
Biological Process
GO:0007612 learning
GO:0007613 memory
GO:0035640 exploration behavior
GO:0040011 locomotion
GO:0048168 regulation of neuronal synaptic plasticity
GO:0050885 neuromuscular process controlling balance
GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity
GO:0070588 calcium ion transmembrane transport
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0030314 junctional membrane complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000154118
View Gene Order
ENSMUSG00000025318
View Gene Order
Cross-References
SwissProt
TrEMBL E1BGY9
UniProt Splice Variant
Entrez Gene 507713
UniGene Bt.35813
RefSeq NM_001205619
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02046226
GenPept
RNA Seq Atlas 507713

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca