Version 5.4
Homo sapiens Gene: FTSJ1
Summary
InnateDB Gene IDBG-63140.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FTSJ1
Gene Name FtsJ RNA methyltransferase homolog 1 (E. coli)
Synonyms CDLIV; MRX44; MRX9; SPB1; TRMT7
Species Homo sapiens
Ensembl Gene ENSG00000068438
Encoded Proteins
IDBP-63142
FtsJ homolog 1 (E. coli)
IDBP-63144
FtsJ homolog 1 (E. coli)
IDBP-236514
FtsJ homolog 1 (E. coli)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the S-adenosylmethionine-binding protein family. It is a nucleolar protein and may be involved in the processing and modification of rRNA. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
This gene encodes a member of the methyltransferase superfamily. The encoded protein localizes to the nucleolus, binds to S-adenosylmethionine, and may be involved in the processing and modification of ribosomal RNA. Mutations in this gene are associated with mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome X:48476021-48486364
Strand Forward strand
Band p11.23
Transcripts
ENST00000019019 ENSP00000019019
ENST00000348411 ENSP00000326948
ENST00000396894 ENSP00000380103
ENST00000492562
ENST00000485486
ENST00000473235
ENST00000487353
ENST00000490202
ENST00000496365
ENST00000466371
ENST00000467954
ENST00000475806
ENST00000489599
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 4 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008168 methyltransferase activity
GO:0008175 tRNA methyltransferase activity
Biological Process
GO:0001510 RNA methylation
GO:0002128 tRNA nucleoside ribose methylation
GO:0002181 cytoplasmic translation
GO:0032259 methylation
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031171
View Gene Order
ENSBTAG00000031829
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.23170
RefSeq NM_001282157 NM_012280 NM_177439 XM_005272595
HUGO
OMIM
CCDS CCDS14294 CCDS14295 CCDS75972
HPRD 06568
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca