Homo sapiens Gene: FTSJ1
Summary
InnateDB Gene IDBG-63140.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FTSJ1
Gene Name FtsJ RNA methyltransferase homolog 1 (E. coli)
Synonyms CDLIV; MRX44; MRX9; SPB1; TRMT7;
Species Homo sapiens
Ensembl Gene ENSG00000068438
Encoded Proteins
FtsJ homolog 1 (E. coli)
FtsJ homolog 1 (E. coli)
FtsJ homolog 1 (E. coli)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the S-adenosylmethionine-binding protein family. It is a nucleolar protein and may be involved in the processing and modification of rRNA. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
This gene encodes a member of the methyltransferase superfamily. The encoded protein localizes to the nucleolus, binds to S-adenosylmethionine, and may be involved in the processing and modification of ribosomal RNA. Mutations in this gene are associated with mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome X:48476021-48486364
Strand Forward strand
Band p11.23
Transcripts
ENST00000019019 ENSP00000019019
ENST00000348411 ENSP00000326948
ENST00000396894 ENSP00000380103
ENST00000492562
ENST00000485486
ENST00000473235
ENST00000487353
ENST00000490202
ENST00000496365
ENST00000466371
ENST00000467954
ENST00000475806
ENST00000489599
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 4 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008168 methyltransferase activity
GO:0008175 tRNA methyltransferase activity
Biological Process
GO:0001510 RNA methylation
GO:0002128 tRNA nucleoside ribose methylation
GO:0002181 cytoplasmic translation
GO:0032259 methylation
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q9UET6
TrEMBL A0A024QYX5
UniProt Splice Variant
Entrez Gene 24140
UniGene Hs.23170
RefSeq NM_012280 NM_001282157 NM_177439 XM_005272595
HUGO HGNC:13254
OMIM 300499
CCDS CCDS14294 CCDS14295 CCDS75972
HPRD 06568
IMGT
EMBL AF063015 AF196972 AJ005892 AK315138 BC023584 CH471224
GenPept AAC33734 AAH23584 BAG37587 CAA06749 EAW50782 EAW50783
RNA Seq Atlas 24140