Version 5.4
Bos taurus Gene: FGL2
Summary
InnateDB Gene IDBG-631421.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FGL2
Gene Name Fibroleukin
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000009717
Encoded Proteins
IDBP-682948
Fibroleukin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000127951:
The protein encoded by this gene is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. This protein may play a role in physiologic functions at mucosal sites. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:44236254-44240215
Strand Forward strand
Band
Transcripts
ENSBTAT00000012815 ENSBTAP00000012815
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016504 peptidase activator activity
Biological Process
GO:0010952 positive regulation of peptidase activity
Cellular Component
GO:0005576 extracellular region
GO:0009986 cell surface
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000127951
View Gene Order
ENSMUSG00000039899
View Gene Order
Cross-References
SwissProt Q29RY7
TrEMBL
UniProt Splice Variant
Entrez Gene 511711
UniGene Bt.76115
RefSeq NM_001046097
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC113335
GenPept AAI13336
RNA Seq Atlas 511711

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca