Version 5.4
Homo sapiens Gene: SPAG11B
Summary
InnateDB Gene IDBG-6315.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPAG11B
Gene Name sperm associated antigen 11B
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000164871
Encoded Proteins
IDBP-6317
sperm associated antigen 11B
IDBP-6319
sperm associated antigen 11B
IDBP-6321
sperm associated antigen 11B
IDBP-6325
sperm associated antigen 11B
IDBP-233008
sperm associated antigen 11B
IDBP-360729
sperm associated antigen 11B
IDBP-586705
sperm associated antigen 11B
IDBP-599450
sperm associated antigen 11B
IDBP-600923
sperm associated antigen 11B
IDBP-812622
sperm associated antigen 11B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes several androgen-dependent, epididymis-specific secretory proteins. The specific functions of these proteins have not been determined, but they are thought to be involved in sperm maturation. Some of the isoforms contain regions of similarity to beta-defensins, a family of antimicrobial peptides. The gene is located on chromosome 8p23 near the defensin gene cluster. Alternative splicing of this gene results in seven transcript variants encoding different isoforms. Two different N-terminal and five different C-terminal protein sequences are encoded by the splice variants. Two additional variants have been described, but their full length sequences have not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:7442684-7463674
Strand Reverse strand
Band p23.1
Transcripts
ENST00000359758 ENSP00000352797
ENST00000361111 ENSP00000354411
ENST00000297498 ENSP00000297498
ENST00000317900 ENSP00000322591
ENST00000398462 ENSP00000381480
ENST00000458665 ENSP00000398550
ENST00000528943 ENSP00000437154
ENST00000528767 ENSP00000432257
ENST00000528168 ENSP00000431230
ENST00000621896 ENSP00000479059
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0006952 defense response
GO:0007283 spermatogenesis
Cellular Component
GO:0005576 extracellular region
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 653423
UniGene
RefSeq NM_016512 NM_058200 NM_058201 NM_058202 NM_058203 NM_058206 NM_058207 XM_005272391 XM_005272392
HUGO HGNC:14534
OMIM 606560
CCDS CCDS47774 CCDS5964 CCDS5965 CCDS5966 CCDS5967
HPRD
IMGT
EMBL AC130360 AF168616 AF168617 AJ628017 AJ635328 AY005129 X67697
GenPept AAF37186 AAF37187 AAG21878 AAG21879 AAG21880 AAG21881 AAG21882 AAG21883 CAA47927 CAF31328 CAG25732
RNA Seq Atlas 10407 653423

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca