Bos taurus Gene: BRD7
Summary
InnateDB Gene IDBG-631618.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BRD7
Gene Name bromodomain-containing protein 7
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000021575
Encoded Proteins
bromodomain-containing protein 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166164:
This gene encodes a protein which is a member of the bromodomain-containing protein family. The product of this gene has been identified as a component of one form of the SWI/SNF chromatin remodeling complex, and as a protein which interacts with p53 and is required for p53-dependent oncogene-induced senescence which prevents tumor growth. Pseudogenes have been described on chromosomes 2, 3, 6, 13 and 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:18810541-18858142
Strand Reverse strand
Band
Transcripts
ENSBTAT00000028747 ENSBTAP00000028747
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 46 interaction(s) predicted by orthology.
Predicted by orthology
Total 46 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0002039 p53 binding
GO:0003713 transcription coactivator activity
GO:0003714 transcription corepressor activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0042393 histone binding
GO:0044212 transcription regulatory region DNA binding
GO:0070577 lysine-acetylated histone binding
Biological Process
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0008285 negative regulation of cell proliferation
GO:0035066 positive regulation of histone acetylation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL A6QLF6
UniProt Splice Variant
Entrez Gene 526153
UniGene Bt.42641
RefSeq NM_001103260 XM_005218615 XM_005218616
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC147947 DAAA02046386 DAAA02046387 DAAA02046388
GenPept AAI47948
RNA Seq Atlas 526153
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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