Version 5.4
Bos taurus Gene: LASS5
Summary
InnateDB Gene IDBG-632409.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LASS5
Gene Name ceramide synthase 5
Synonyms LASS5
Species Bos taurus
Ensembl Gene ENSBTAG00000017395
Encoded Proteins
IDBP-684016
LAG1 longevity assurance homolog 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000139624:
Gene Information
Type Protein coding
Genomic Location Chromosome 5:29905581-29935323
Strand Forward strand
Band
Transcripts
ENSBTAT00000029121 ENSBTAP00000029121
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
GO:0050291 sphingosine N-acyltransferase activity
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0030148 sphingolipid biosynthetic process
GO:0046513 ceramide biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0005783 endoplasmic reticulum
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000139624
View Gene Order
ENSMUSG00000023021
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_115810
Sphingolipid de novo biosynthesis pathway
REACT_19323
Sphingolipid metabolism pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_111217
Metabolism pathway
REACT_198151
Sphingolipid de novo biosynthesis pathway
REACT_188937
Metabolism pathway
REACT_245163
Sphingolipid metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
KEGG
hsa00600
Sphingolipid metabolism pathway
mmu00600
Sphingolipid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL A6QQ18
UniProt Splice Variant
Entrez Gene 530776
UniGene Bt.26667
RefSeq NM_001102132
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC149597 DAAA02012932
GenPept AAI49598
RNA Seq Atlas 530776

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca