Bos taurus Gene: COX14
Summary
InnateDB Gene IDBG-632411.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol COX14
Gene Name Cytochrome c oxidase assembly protein COX14
Synonyms C12orf62; C5H12orf62
Species Bos taurus
Ensembl Gene ENSBTAG00000000808
Encoded Proteins
Uncharacterized protein C12orf62 homolog
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000178449:
This gene encodes a small single-pass transmembrane protein that localizes to mitochondria. This protein may play a role in coordinating the early steps of cytochrome c oxidase (COX; also known as complex IV) subunit assembly and, in particular, the synthesis and assembly of the COX I subunit of the holoenzyme. Mutations in this gene have been associated with mitochondrial complex IV deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:29952087-29956382
Strand Reverse strand
Band
Transcripts
ENSBTAT00000001069 ENSBTAP00000001069
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0033617 mitochondrial respiratory chain complex IV assembly
Cellular Component
GO:0005739 mitochondrion
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031966 mitochondrial membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
Orphan transporters pathway
The citric acid (TCA) cycle and respiratory electron transport pathway
Transmembrane transport of small molecules pathway
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
Metabolism pathway
Respiratory electron transport pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Respiratory electron transport pathway
Transmembrane transport of small molecules pathway
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
Orphan transporters pathway
The citric acid (TCA) cycle and respiratory electron transport pathway
Metabolism pathway
The citric acid (TCA) cycle and respiratory electron transport pathway
Orphan transporters pathway
Respiratory electron transport pathway
Metabolism pathway
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
Transmembrane transport of small molecules pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q1RMH3
TrEMBL
UniProt Splice Variant
Entrez Gene 768048
UniGene
RefSeq NM_001195064
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC114898
GenPept AAI14899
RNA Seq Atlas 768048