Version 5.4
Homo sapiens Gene: CAP2
Summary
InnateDB Gene IDBG-63271.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CAP2
Gene Name CAP, adenylate cyclase-associated protein, 2 (yeast)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000112186
Encoded Proteins
IDBP-63273
CAP, adenylate cyclase-associated protein, 2 (yeast)
IDBP-63275
CAP, adenylate cyclase-associated protein, 2 (yeast)
IDBP-479921
CAP, adenylate cyclase-associated protein, 2 (yeast)
IDBP-475729
CAP, adenylate cyclase-associated protein, 2 (yeast)
IDBP-482867
CAP, adenylate cyclase-associated protein, 2 (yeast)
IDBP-476162
CAP, adenylate cyclase-associated protein, 2 (yeast)
IDBP-480565
CAP, adenylate cyclase-associated protein, 2 (yeast)
IDBP-807450
CAP, adenylate cyclase-associated protein, 2 (yeast)
IDBP-807451
CAP, adenylate cyclase-associated protein, 2 (yeast)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene was identified by its similarity to the gene for human adenylyl cyclase-associated protein. The function of the protein encoded by this gene is unknown. However, the protein appears to be able to interact with adenylyl cyclase-associated protein and actin. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:17393216-17557792
Strand Forward strand
Band p22.3
Transcripts
ENST00000229922 ENSP00000229922
ENST00000378990 ENSP00000368275
ENST00000489374 ENSP00000417705
ENST00000493172 ENSP00000417208
ENST00000479291 ENSP00000420615
ENST00000465994 ENSP00000418604
ENST00000476263 ENSP00000419906
ENST00000611958 ENSP00000482279
ENST00000616440 ENSP00000483435
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
Biological Process
GO:0000902 cell morphogenesis
GO:0007010 cytoskeleton organization
GO:0007163 establishment or maintenance of cell polarity
GO:0007165 signal transduction
GO:0007190 activation of adenylate cyclase activity
GO:0007411 axon guidance
Cellular Component
GO:0005886 plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000021373
View Gene Order
ENSBTAG00000016924
Not yet available
Pathways
NETPATH
REACTOME
REACT_19230
Role of Abl in Robo-Slit signaling pathway
REACT_19351
Signaling by Robo receptor pathway
REACT_111045
Developmental Biology pathway
REACT_18266
Axon guidance pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL B7Z1C4
UniProt Splice Variant
Entrez Gene 10486
UniGene Hs.132902 Hs.605285
RefSeq NM_006366
HUGO HGNC:20039
OMIM
CCDS CCDS4539
HPRD 10808
IMGT
EMBL AK293134 AL034372 AL138824
GenPept BAH11460
RNA Seq Atlas 10486

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca