Bos taurus Gene: AMPD3
Summary
InnateDB Gene IDBG-633321.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AMPD3
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000015821
Encoded Proteins
adenosine monophosphate deaminase 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000133805:
This gene encodes a member of the AMP deaminase gene family. The encoded protein is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. This gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. Mutations in this gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:42759305-42796464
Strand Reverse strand
Band
Transcripts
ENSBTAT00000021018 ENSBTAP00000021018
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003876 AMP deaminase activity
GO:0019239 deaminase activity
Biological Process
GO:0006188 IMP biosynthetic process
GO:0032264 IMP salvage
GO:0046031 ADP metabolic process
GO:0046033 AMP metabolic process
GO:0046034 ATP metabolic process
GO:0097009 energy homeostasis
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Purine metabolism pathway
Purine salvage pathway
Metabolism of nucleotides pathway
Metabolism pathway
Purine metabolism pathway
Metabolism pathway
Purine salvage pathway
Metabolism of nucleotides pathway
KEGG
Purine metabolism pathway
Purine metabolism pathway
INOH
Purine nucleotides nucleosides metabolism pathway
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL E1BA23
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq
HUGO HGNC:470
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02040712 DAAA02040713
GenPept
RNA Seq Atlas