Version 5.4
| Bos taurus Gene: CLCN7 | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Summary | |||||||||||||||||
| InnateDB Gene | IDBG-634451.3 | ||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||
| Gene Symbol | CLCN7 | ||||||||||||||||
| Gene Name | H(+)/Cl(-) exchange transporter 7 | ||||||||||||||||
| Synonyms | CLC-7; CLC7 | ||||||||||||||||
| Species | Bos taurus | ||||||||||||||||
| Ensembl Gene | ENSBTAG00000015889 | ||||||||||||||||
| Encoded Proteins |
H(+)/Cl(-) exchange transporter 7
|
||||||||||||||||
| Protein Structure |
|
||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||
| Entrez Gene | |||||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000103249:
The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood. [provided by RefSeq, Jul 2008] |
||||||||||||||||
| Gene Information | |||||||||||||||||
| Type | Protein coding | ||||||||||||||||
| Genomic Location | Chromosome 25:1135571-1156102 | ||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||
| Band | |||||||||||||||||
| Transcripts |
|
||||||||||||||||
| Interactions | |||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
|
||||||||||||||||
| Gene Ontology | |||||||||||||||||
Molecular Function |
|
||||||||||||||||
| Biological Process |
|
||||||||||||||||
| Cellular Component |
|
||||||||||||||||
| Orthologs | |||||||||||||||||
|
Species
Homo sapiens
Mus musculus
|
Gene ID
Gene Order
|
||||||||||||||||
| Pathways | |||||||||||||||||
| NETPATH | |||||||||||||||||
| REACTOME |
Ion channel transport pathway
Transmembrane transport of small molecules pathway
Stimuli-sensing channels pathway
|
||||||||||||||||
| KEGG | |||||||||||||||||
| INOH | |||||||||||||||||
| PID NCI | |||||||||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||||||||
| NETPATH | |||||||||||||||||
| REACTOME |
Stimuli-sensing channels pathway
Transmembrane transport of small molecules pathway
Ion channel transport pathway
Stimuli-sensing channels pathway
Ion channel transport pathway
Transmembrane transport of small molecules pathway
|
||||||||||||||||
| KEGG | |||||||||||||||||
| INOH | |||||||||||||||||
| PID NCI | |||||||||||||||||
| Cross-References | |||||||||||||||||
| SwissProt | Q4PKH3 | ||||||||||||||||
| TrEMBL | M5FKE3 | ||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||
| Entrez Gene | 513545 | ||||||||||||||||
| UniGene | Bt.6124 | ||||||||||||||||
| RefSeq | NM_001025331 XM_005224435 | ||||||||||||||||
| HUGO | |||||||||||||||||
| OMIM | |||||||||||||||||
| CCDS | |||||||||||||||||
| HPRD | |||||||||||||||||
| IMGT | |||||||||||||||||
| EMBL | DQ073465 GJ062847 | ||||||||||||||||
| GenPept | AAY82470 DAA15577 | ||||||||||||||||
| RNA Seq Atlas | 513545 | ||||||||||||||||