InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: BT.87687

Summary

InnateDB Gene

IDBG-635688.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.87687

Gene Name

epoxide hydrolase 2

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000015241

Encoded Proteins

IDBP-687542

epoxide hydrolase 2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000120915:
This gene encodes a member of the epoxide hydrolase family. The protein, found in both the cytosol and peroxisomes, binds to specific epoxides and converts them to the corresponding dihydrodiols. Mutations in this gene have been associated with familial hypercholesterolemia. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 8:75908165-75977482

Strand

Forward strand

Band

Transcripts

ENSBTAT00000020272

ENSBTAP00000020272

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000287	magnesium ion binding
GO:0003824	catalytic activity
GO:0004301	epoxide hydrolase activity
GO:0005102	receptor binding
GO:0015643	toxic substance binding
GO:0016787	hydrolase activity
GO:0016791	phosphatase activity
GO:0042577	lipid phosphatase activity

Biological Process

GO:0008152	metabolic process
GO:0010628	positive regulation of gene expression
GO:0016311	dephosphorylation
GO:0042632	cholesterol homeostasis
GO:0046272	stilbene catabolic process
GO:0046839	phospholipid dephosphorylation
GO:0090181	regulation of cholesterol metabolic process