Version 5.4
Bos taurus Gene: RCN1
Summary
InnateDB Gene IDBG-636221.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RCN1
Gene Name reticulocalbin-1 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000047362
Encoded Proteins
IDBP-688132
reticulocalbin 1, EF-hand calcium binding domain
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000049449:
Reticulocalbin 1 is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. High conservation of amino acid residues outside of these motifs, in comparison to mouse reticulocalbin, is consistent with a possible biochemical function besides that of calcium binding. In human endothelial and prostate cancer cell lines this protein localizes to the plasma membrane.[provided by RefSeq, Jan 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:63656459-63663593
Strand Forward strand
Band
Transcripts
ENSBTAT00000063521 ENSBTAP00000056127
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.
Predicted by orthology
Total 31 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0001701 in utero embryonic development
GO:0043010 camera-type eye development
Cellular Component
GO:0005783 endoplasmic reticulum
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000049449
View Gene Order
ENSMUSG00000005973
View Gene Order
Cross-References
SwissProt
TrEMBL A4IF88 G3N2L2
UniProt Splice Variant
Entrez Gene 281445
UniGene Bt.96665
RefSeq NM_001103221
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC134456 DAAA02041232
GenPept AAI34457
RNA Seq Atlas 281445
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

(Move your mouse over the image to view a more detailed version)

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca