Version 5.4
| Bos taurus Gene: PMM2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Summary | |||||||||
| InnateDB Gene | IDBG-636627.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | PMM2 | ||||||||
| Gene Name | Phosphomannomutase 2 | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000001440 | ||||||||
| Encoded Proteins |
Phosphomannomutase 2
|
||||||||
| Protein Structure |
|
||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000140650:
The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. Mutations in this gene have been shown to cause defects in glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein syndrome type I. [provided by RefSeq, Jul 2008] |
||||||||
| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 25:7700704-7730822 | ||||||||
| Strand | Forward strand | ||||||||
| Band | |||||||||
| Transcripts |
|
||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
|
||||||||
| Gene Ontology | |||||||||
Molecular Function |
|
||||||||
| Biological Process |
|
||||||||
| Cellular Component |
|
||||||||
| Orthologs | |||||||||
|
Species
Homo sapiens
Mus musculus
|
Gene ID
Gene Order
|
||||||||
| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
Asparagine N-linked glycosylation pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Synthesis of substrates in N-glycan biosythesis pathway
Synthesis of GDP-mannose pathway
|
||||||||
| KEGG | |||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Synthesis of GDP-mannose pathway
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Asparagine N-linked glycosylation pathway
Post-translational protein modification pathway
Synthesis of substrates in N-glycan biosythesis pathway
Metabolism of proteins pathway
Synthesis of substrates in N-glycan biosythesis pathway
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Synthesis of GDP-mannose pathway
Asparagine N-linked glycosylation pathway
|
||||||||
| KEGG |
Amino sugar and nucleotide sugar metabolism pathway
Fructose and mannose metabolism pathway
Amino sugar and nucleotide sugar metabolism pathway
Fructose and mannose metabolism pathway
|
||||||||
| INOH |
Fructose Mannose metabolism pathway
|
||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | Q3SZJ9 | ||||||||
| TrEMBL | M5FJZ1 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 510978 | ||||||||
| UniGene | Bt.63538 Bt.88758 | ||||||||
| RefSeq | NM_001035095 XM_005224423 XM_005224424 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | BC102817 GJ062847 | ||||||||
| GenPept | AAI02818 DAA15570 | ||||||||
| RNA Seq Atlas | 510978 | ||||||||