InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: RPL31

Summary

InnateDB Gene

IDBG-63682.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RPL31

Gene Name

ribosomal protein L31

Synonyms

L31

Species

Homo sapiens

Ensembl Gene

ENSG00000071082

Encoded Proteins

IDBP-63684

ribosomal protein L31

IDBP-295134

ribosomal protein L31

IDBP-295149

ribosomal protein L31

IDBP-295155

ribosomal protein L31

IDBP-295142

ribosomal protein L31

IDBP-295147

ribosomal protein L31

IDBP-295152

ribosomal protein L31

IDBP-295150

ribosomal protein L31

IDBP-383685

ribosomal protein L31

IDBP-383687

ribosomal protein L31

IDBP-383688

ribosomal protein L31

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L31E family of ribosomal proteins. It is located in the cytoplasm. Higher levels of expression of this gene in familial adenomatous polyps compared to matched normal tissues have been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:101001715-101024032

Strand

Forward strand

Band

q11.2

Transcripts

ENST00000264258	ENSP00000264258
ENST00000409028	ENSP00000386717
ENST00000409038	ENSP00000386737
ENST00000409650	ENSP00000386271
ENST00000409733	ENSP00000386681
ENST00000409320	ENSP00000387163
ENST00000409000	ENSP00000387120
ENST00000409711	ENSP00000387112
ENST00000419276	ENSP00000402450
ENST00000456292	ENSP00000412976
ENST00000441435	ENSP00000408172

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 132 experimentally validated interaction(s) in this database.

Experimentally validated
Total	132 [view]
Protein-Protein	131 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0006412	translation
GO:0006413	translational initiation
GO:0006414	translational elongation
GO:0006415	translational termination
GO:0006614	SRP-dependent cotranslational protein targeting to membrane
GO:0010467	gene expression
GO:0016032	viral process
GO:0016070	RNA metabolic process
GO:0016071	mRNA metabolic process
GO:0019058	viral life cycle
GO:0019083	viral transcription
GO:0044267	cellular protein metabolic process

Cellular Component

GO:0005622	intracellular
GO:0005829	cytosol
GO:0005840	ribosome
GO:0016020	membrane
GO:0022625	cytosolic large ribosomal subunit
GO:0070062	extracellular vesicular exosome