Bos taurus Gene: STAM | |||||||
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Summary | |||||||
InnateDB Gene | IDBG-638370.3 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | STAM | ||||||
Gene Name | signal transducing adapter molecule 1 | ||||||
Synonyms | |||||||
Species | Bos taurus | ||||||
Ensembl Gene | ENSBTAG00000002658 | ||||||
Encoded Proteins |
signal transducing adapter molecule 1
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Protein Structure | |||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||
Entrez Gene | |||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136738:
This gene encodes a member of the signal-transducing adaptor molecule family. These proteins mediate downstream signaling of cytokine receptors and also play a role in ER to Golgi trafficking by interacting with the coat protein II complex. The encoded protein also associates with hepatocyte growth factor-regulated substrate to form the endosomal sorting complex required for transport-0 (ESCRT-0), which sorts ubiquitinated membrane proteins to the ESCRT-1 complex for lysosomal degradation. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011] |
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Gene Information | |||||||
Type | Protein coding | ||||||
Genomic Location | Chromosome 13:32390175-32445156 | ||||||
Strand | Forward strand | ||||||
Band | |||||||
Transcripts |
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Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 45 interaction(s) predicted by orthology.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||
NETPATH |
EGFR1 pathway
IL2 pathway
IL4 pathway
IL-7 pathway
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REACTOME |
EGFR downregulation pathway
Signaling by EGFR pathway
Endosomal Sorting Complex Required For Transport (ESCRT) pathway
Signaling by EGFR in Cancer pathway
Signal Transduction pathway
Disease pathway
Membrane Trafficking pathway
EGFR downregulation pathway
Disease pathway
Membrane Trafficking pathway
Endosomal Sorting Complex Required For Transport (ESCRT) pathway
Signaling by EGFR pathway
Signal Transduction pathway
Signaling by EGFR in Cancer pathway
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KEGG |
Jak-STAT signaling pathway pathway
Endocytosis pathway
Jak-STAT signaling pathway pathway
Endocytosis pathway
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INOH | |||||||
PID NCI | |||||||
Cross-References | |||||||
SwissProt | |||||||
TrEMBL | |||||||
UniProt Splice Variant | |||||||
Entrez Gene | |||||||
UniGene | Bt.34503 | ||||||
RefSeq | NM_001076842 | ||||||
HUGO | |||||||
OMIM | |||||||
CCDS | |||||||
HPRD | |||||||
IMGT | |||||||
EMBL | |||||||
GenPept | |||||||
RNA Seq Atlas | |||||||