Bos taurus Gene: CA5B
Summary
InnateDB Gene IDBG-638891.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CA5B
Gene Name carbonic anhydrase 5B, mitochondrial
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000020418
Encoded Proteins
carbonic anhydrase 5B, mitochondrial
carbonic anhydrase 5B, mitochondrial
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000169239:
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VB is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA, CA VA. It has a wider tissue distribution than CA VA, which is restricted to the liver. The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles. [provided by RefSeq, Jul 2008]
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VB is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA, CA VA. It has a wider tissue distribution than CA VA, which is restricted to the liver. The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:135022449-135049835
Strand Reverse strand
Band
Transcripts
ENSBTAT00000027210 ENSBTAP00000027210
ENSBTAT00000044236 ENSBTAP00000041746
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004089 carbonate dehydratase activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006730 one-carbon metabolic process
GO:0008152 metabolic process
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Reversible hydration of carbon dioxide pathway
Metabolism pathway
Metabolism pathway
Reversible hydration of carbon dioxide pathway
KEGG
Nitrogen metabolism pathway
Nitrogen metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1N5D1 Q0V890
UniProt Splice Variant
Entrez Gene 514494
UniGene Bt.43187
RefSeq NM_001080908 XM_005228435
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BT026329 DAAA02074879
GenPept ABG81485
RNA Seq Atlas 514494