Bos taurus Gene: BT.62405 | |||||||||||||||
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Summary | |||||||||||||||
InnateDB Gene | IDBG-639486.3 | ||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||
Gene Symbol | BT.62405 | ||||||||||||||
Gene Name | zinc finger protein Aiolos | ||||||||||||||
Synonyms | |||||||||||||||
Species | Bos taurus | ||||||||||||||
Ensembl Gene | ENSBTAG00000011003 | ||||||||||||||
Encoded Proteins |
zinc finger protein Aiolos
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Protein Structure | |||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||
Entrez Gene | |||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000161405:
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012] |
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Gene Information | |||||||||||||||
Type | Protein coding | ||||||||||||||
Genomic Location | Chromosome 19:40779127-40864311 | ||||||||||||||
Strand | Reverse strand | ||||||||||||||
Band | |||||||||||||||
Transcripts |
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Interactions | |||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||||
NETPATH | |||||||||||||||
REACTOME | |||||||||||||||
KEGG | |||||||||||||||
INOH | |||||||||||||||
PID NCI |
IL2-mediated signaling events
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Cross-References | |||||||||||||||
SwissProt | |||||||||||||||
TrEMBL | G5E5E5 | ||||||||||||||
UniProt Splice Variant | |||||||||||||||
Entrez Gene | 540676 | ||||||||||||||
UniGene | Bt.62405 | ||||||||||||||
RefSeq | NM_001081613 | ||||||||||||||
HUGO | HGNC:13178 | ||||||||||||||
OMIM | |||||||||||||||
CCDS | |||||||||||||||
HPRD | |||||||||||||||
IMGT | |||||||||||||||
EMBL | DAAA02049124 DAAA02049125 DAAA02049126 DAAA02049127 | ||||||||||||||
GenPept | |||||||||||||||
RNA Seq Atlas | 540676 | ||||||||||||||