Bos taurus Gene: HAO1
Summary
InnateDB Gene IDBG-639976.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HAO1
Gene Name hydroxyacid oxidase 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000019811
Encoded Proteins
hydroxyacid oxidase 1
hydroxyacid oxidase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101323:
This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:51110902-51173199
Strand Reverse strand
Band
Transcripts
ENSBTAT00000061291 ENSBTAP00000053733
ENSBTAT00000056526 ENSBTAP00000048395
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0003973 (S)-2-hydroxy-acid oxidase activity
GO:0005102 receptor binding
GO:0008891 glycolate oxidase activity
GO:0010181 FMN binding
GO:0015930 glutamate synthase activity
GO:0016491 oxidoreductase activity
GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors
Biological Process
GO:0001561 fatty acid alpha-oxidation
GO:0006537 glutamate biosynthetic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005777 peroxisome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
SSD Ortholog
Ortholog supports species divergence
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Metabolism of amino acids and derivatives pathway
Glyoxylate metabolism pathway
Metabolism pathway
Metabolism pathway
Metabolism of amino acids and derivatives pathway
Glyoxylate metabolism pathway
KEGG
Glyoxylate and dicarboxylate metabolism pathway
Peroxisome pathway
Glyoxylate and dicarboxylate metabolism pathway
Peroxisome pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.103776
RefSeq NM_001079781
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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