Homo sapiens Gene: PAAF1
Summary
InnateDB Gene IDBG-64021.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PAAF1
Gene Name proteasomal ATPase-associated factor 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000175575
Encoded Proteins
proteasomal ATPase-associated factor 1
proteasomal ATPase-associated factor 1
proteasomal ATPase-associated factor 1
proteasomal ATPase-associated factor 1
proteasomal ATPase-associated factor 1
proteasomal ATPase-associated factor 1
proteasomal ATPase-associated factor 1
proteasomal ATPase-associated factor 1
proteasomal ATPase-associated factor 1
proteasomal ATPase-associated factor 1
proteasomal ATPase-associated factor 1
proteasomal ATPase-associated factor 1
proteasomal ATPase-associated factor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a WD repeat-containing protein involved in regulation of association of proteasome components. During HIV infection, the encoded protein is thought to promote provirus transcription through recruitment of the 19S regulatory complex. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:73876699-73927745
Strand Forward strand
Band q13.4
Transcripts
ENST00000381783
ENST00000310571 ENSP00000311665
ENST00000376384 ENSP00000365564
ENST00000504441 ENSP00000439747
ENST00000541951 ENSP00000441333
ENST00000543814 ENSP00000438894
ENST00000535604 ENSP00000438789
ENST00000542293 ENSP00000439143
ENST00000536003 ENSP00000438124
ENST00000544552 ENSP00000441494
ENST00000546039 ENSP00000439877
ENST00000543079
ENST00000536582 ENSP00000443473
ENST00000544909 ENSP00000438071
ENST00000540659 ENSP00000442434
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 43 experimentally validated interaction(s) in this database.
Experimentally validated
Total 43 [view]
Protein-Protein 42 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0016032 viral process
Cellular Component
GO:0000502 proteasome complex
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q9BRP4
TrEMBL A0A024R5N4 F5H103 F5H3E9 F5H3I1
UniProt Splice Variant
Entrez Gene 80227
UniGene Hs.525017 Hs.598189 Hs.635189
RefSeq NM_001267803 NM_001267804 NM_001267805 NM_001267806 NM_025155 XM_005274308
HUGO HGNC:25687
OMIM
CCDS CCDS58157 CCDS58158 CCDS8226
HPRD 07761
IMGT
EMBL AF087895 AK021910 AK222501 AK298258 AK316394 AP002770 BC006142 BC021541 BC028628 CH471076
GenPept AAH06142 AAH21541 AAH28628 AAP97194 BAB13933 BAD96221 BAG60522 BAH14765 EAW74917 EAW74919
RNA Seq Atlas 80227