Bos taurus Gene: VAX1
Summary
InnateDB Gene IDBG-640236.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol VAX1
Gene Name ventral anterior homeobox 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000013875
Encoded Proteins
ventral anterior homeobox 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000148704:
This gene encodes a homeo-domain containing protein from a class of homeobox transcription factors which are conserved in vertebrates. Genes of this family are involved in the regulation of body development and morphogenesis. The most conserved genes, called HOX genes are found in special gene clusters. This gene belongs to the VAX subfamily and lies in the vicinity of the EMX homeobox gene family. Another member of VAX family is located on chromosome 2. The encoded protein may play an important role in the development of anterior ventral forebrain and visual system. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 26:37796165-37801021
Strand Reverse strand
Band
Transcripts
ENSBTAT00000032764 ENSBTAP00000032693
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0031490 chromatin DNA binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001764 neuron migration
GO:0006355 regulation of transcription, DNA-templated
GO:0007399 nervous system development
GO:0007406 negative regulation of neuroblast proliferation
GO:0007411 axon guidance
GO:0007417 central nervous system development
GO:0007420 brain development
GO:0030154 cell differentiation
GO:0035914 skeletal muscle cell differentiation
GO:0043010 camera-type eye development
GO:0060021 palate development
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL E1B853
UniProt Splice Variant
Entrez Gene 782056
UniGene Bt.106422
RefSeq NM_001191142
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02059342 DAAA02059343
GenPept
RNA Seq Atlas 782056