InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: PRPF6

Summary

InnateDB Gene

IDBG-640419.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PRPF6

Gene Name

Pre-mRNA-processing factor 6

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000011656

Encoded Proteins

IDBP-692683

pre-mRNA-processing factor 6

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101161:
The protein encoded by this gene appears to be involved in pre-mRNA splicing, possibly acting as a bridging factor between U5 and U4/U6 snRNPs in formation of the spliceosome. The encoded protein also can bind androgen receptor, providing a link between transcriptional activation and splicing. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 13:54308647-54343470

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000015480

ENSBTAP00000015480

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 59 interaction(s) predicted by orthology.

Predicted by orthology
Total	59 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003713	transcription coactivator activity
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0043021	ribonucleoprotein complex binding
GO:0044822	poly(A) RNA binding
GO:0050681	androgen receptor binding

Biological Process

GO:0000398	mRNA splicing, via spliceosome
GO:0006396	RNA processing
GO:0006397	mRNA processing
GO:0006403	RNA localization
GO:0008380	RNA splicing
GO:0045944	positive regulation of transcription from RNA polymerase II promoter

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005681	spliceosomal complex
GO:0005682	U5 snRNP
GO:0016020	membrane
GO:0016607	nuclear speck
GO:0046540	U4/U6 x U5 tri-snRNP complex
GO:0071001	U4/U6 snRNP
GO:0071013	catalytic step 2 spliceosome