InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: BT.39594

Summary

InnateDB Gene

IDBG-640860.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.39594

Gene Name

WD repeat-containing protein 5

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000047031

Encoded Proteins

IDBP-693169

WD repeat-containing protein 5

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000196363:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 11:104929237-104939742

Strand

Forward strand

Band

Transcripts

ENSBTAT00000066090

ENSBTAP00000056448

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 133 interaction(s) predicted by orthology.

Predicted by orthology
Total	133 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0042800	histone methyltransferase activity (H3-K4 specific)
GO:0043995	histone acetyltransferase activity (H4-K5 specific)
GO:0043996	histone acetyltransferase activity (H4-K8 specific)
GO:0046972	histone acetyltransferase activity (H4-K16 specific)

Biological Process

GO:0001501	skeletal system development
GO:0043966	histone H3 acetylation
GO:0043981	histone H4-K5 acetylation
GO:0043982	histone H4-K8 acetylation
GO:0043984	histone H4-K16 acetylation
GO:0045722	positive regulation of gluconeogenesis
GO:0051568	histone H3-K4 methylation

Cellular Component

GO:0000123	histone acetyltransferase complex
GO:0005622	intracellular
GO:0005634	nucleus
GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex
GO:0035097	histone methyltransferase complex
GO:0048188	Set1C/COMPASS complex
GO:0071339	MLL1 complex