Version 5.4
Bos taurus Gene: BT.25341
Summary
InnateDB Gene IDBG-641374.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.25341
Gene Name phosphatidylinositol 4-kinase type 2-beta
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000006492
Encoded Proteins
IDBP-693739
phosphatidylinositol 4-kinase type 2-beta
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000038210:
Phosphatidylinositol 4-kinases (PI4Ks) phosphorylate phosphatidylinositol to generate phosphatidylinositol 4-phosphate (PIP), an immediate precursor of several important signaling and scaffolding molecules. PIP itself may also have direct functional and structural roles. PI4K2B is a primarily cytosolic PI4K that is recruited to membranes, where it stimulates phosphatidylinositol 4,5-bisphosphate synthesis (Wei et al., 2002 [PubMed 12324459]).[supplied by OMIM, Jun 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:46355300-46391439
Strand Forward strand
Band
Transcripts
ENSBTAT00000047316 ENSBTAP00000044532
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016773 phosphotransferase activity, alcohol group as acceptor
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000038210
View Gene Order
ENSMUSG00000029186
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_121025
Synthesis of PIPs at the plasma membrane pathway
REACT_120756
Synthesis of PIPs at the early endosome membrane pathway
REACT_121168
Synthesis of PIPs at the ER membrane pathway
REACT_120836
Synthesis of PIPs at the Golgi membrane pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_121175
PI Metabolism pathway
REACT_120870
Phospholipid metabolism pathway
REACT_111217
Metabolism pathway
REACT_198975
Synthesis of PIPs at the early endosome membrane pathway
REACT_198973
Synthesis of PIPs at the plasma membrane pathway
REACT_198970
Synthesis of PIPs at the Golgi membrane pathway
REACT_198971
Synthesis of PIPs at the ER membrane pathway
REACT_199016
PI Metabolism pathway
REACT_188937
Metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_188643
Phospholipid metabolism pathway
KEGG
hsa00562
Inositol phosphate metabolism pathway
hsa04070
Phosphatidylinositol signaling system pathway
mmu04070
Phosphatidylinositol signaling system pathway
mmu00562
Inositol phosphate metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MK34
UniProt Splice Variant
Entrez Gene 521790
UniGene Bt.25341
RefSeq NM_001102064 XM_005207773
HUGO HGNC:18215
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02017162
GenPept
RNA Seq Atlas 521790

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca