Homo sapiens Gene: CDKAL1
Summary
InnateDB Gene IDBG-64189.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CDKAL1
Gene Name CDK5 regulatory subunit associated protein 1-like 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000145996
Encoded Proteins
CDK5 regulatory subunit associated protein 1-like 1
CDK5 regulatory subunit associated protein 1-like 1
CDK5 regulatory subunit associated protein 1-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the methylthiotransferase family. The function of this gene is not known. Genome-wide association studies have linked single nucleotide polymorphisms in an intron of this gene with susceptibilty to type 2 diabetes. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:20534457-21232404
Strand Forward strand
Band p22.3
Transcripts
ENST00000274695 ENSP00000274695
ENST00000378610 ENSP00000367873
ENST00000476517
ENST00000613575 ENSP00000481755
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 6 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016740 transferase activity
GO:0035598 N6-threonylcarbomyladenosine methylthiotransferase activity
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0008150 biological_process
GO:0009451 RNA modification
GO:0035600 tRNA methylthiolation
GO:0043412 macromolecule modification
GO:1990145 maintenance of translational fidelity
Cellular Component
GO:0005575 cellular_component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005791 rough endoplasmic reticulum
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_017774 XM_006715127 XM_006715128
HUGO
OMIM
CCDS CCDS4546
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas