Bos taurus Gene: TSG-6 | |||||||
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Summary | |||||||
InnateDB Gene | IDBG-642045.3 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | TSG-6 | ||||||
Gene Name | tumor necrosis factor-inducible gene 6 protein precursor | ||||||
Synonyms | tsg-6 | ||||||
Species | Bos taurus | ||||||
Ensembl Gene | ENSBTAG00000007239 | ||||||
Encoded Proteins |
tumor necrosis factor-inducible gene 6 protein
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Protein Structure | |||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||
Entrez Gene | |||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000123610:
The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.[provided by RefSeq, Dec 2010] |
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Gene Information | |||||||
Type | Protein coding | ||||||
Genomic Location | Chromosome 2:44850892-44867293 | ||||||
Strand | Reverse strand | ||||||
Band | |||||||
Transcripts |
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Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Cross-References | |||||||
SwissProt | |||||||
TrEMBL | Q5W1C4 | ||||||
UniProt Splice Variant | |||||||
Entrez Gene | 493710 | ||||||
UniGene | Bt.109474 | ||||||
RefSeq | NM_001007813 | ||||||
HUGO | |||||||
OMIM | |||||||
CCDS | |||||||
HPRD | |||||||
IMGT | |||||||
EMBL | AJ854251 BC151789 DAAA02004607 | ||||||
GenPept | AAI51790 CAH74219 | ||||||
RNA Seq Atlas | 493710 | ||||||