Version 5.4
Bos taurus Gene: DPP10
Summary
InnateDB Gene IDBG-642332.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DPP10
Gene Name inactive dipeptidyl peptidase 10
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000005235
Encoded Proteins
IDBP-694789
inactive dipeptidyl peptidase 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000175497:
This gene encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Mutations in this gene have been associated with asthma. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:67935914-68111066
Strand Forward strand
Band
Transcripts
ENSBTAT00000006894 ENSBTAP00000006894
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000175497
View Gene Order
ENSMUSG00000036815
View Gene Order
Cross-References
SwissProt
TrEMBL A0JNH8 F1MM30
UniProt Splice Variant
Entrez Gene 617222
UniGene Bt.111370
RefSeq NM_001078070
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC126689 DAAA02005111 DAAA02005112 DAAA02005113 DAAA02005114 DAAA02005115 DAAA02005116 DAAA02005117 DAAA02005118 DAAA02005119
GenPept AAI26690
RNA Seq Atlas 617222

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca