Bos taurus Gene: RCHY1 | |||||||||||||||
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Summary | |||||||||||||||
InnateDB Gene | IDBG-643046.3 | ||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||
Gene Symbol | RCHY1 | ||||||||||||||
Gene Name | RING finger and CHY zinc finger domain-containing protein 1 | ||||||||||||||
Synonyms | |||||||||||||||
Species | Bos taurus | ||||||||||||||
Ensembl Gene | ENSBTAG00000007189 | ||||||||||||||
Encoded Proteins |
RING finger and CHY zinc finger domain-containing protein 1
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Protein Structure | |||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||
Entrez Gene | |||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163743:
The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including TP53, HDAC1 and CDKN1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011] The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including tumor protein 53, histone deacetylase 1, and cyclin-dependent kinase inhibitor 1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2013] |
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Gene Information | |||||||||||||||
Type | Protein coding | ||||||||||||||
Genomic Location | Chromosome 6:92061508-92076962 | ||||||||||||||
Strand | Reverse strand | ||||||||||||||
Band | |||||||||||||||
Transcripts |
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Interactions | |||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 50 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||||
NETPATH |
AndrogenReceptor pathway
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REACTOME |
Antigen processing: Ubiquitination & Proteasome degradation pathway
Adaptive Immune System pathway
Immune System pathway
Class I MHC mediated antigen processing & presentation pathway
Class I MHC mediated antigen processing & presentation pathway
Immune System pathway
Antigen processing: Ubiquitination & Proteasome degradation pathway
Adaptive Immune System pathway
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KEGG |
Ubiquitin mediated proteolysis pathway
p53 signaling pathway pathway
Ubiquitin mediated proteolysis pathway
p53 signaling pathway pathway
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INOH | |||||||||||||||
PID NCI |
Direct p53 effectors
p53 pathway
p73 transcription factor network
Regulation of Androgen receptor activity
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Cross-References | |||||||||||||||
SwissProt | |||||||||||||||
TrEMBL | A4IFE2 | ||||||||||||||
UniProt Splice Variant | |||||||||||||||
Entrez Gene | 540733 | ||||||||||||||
UniGene | Bt.13497 | ||||||||||||||
RefSeq | NM_001083754 | ||||||||||||||
HUGO | |||||||||||||||
OMIM | |||||||||||||||
CCDS | |||||||||||||||
HPRD | |||||||||||||||
IMGT | |||||||||||||||
EMBL | BC134539 DAAA02018118 | ||||||||||||||
GenPept | AAI34540 | ||||||||||||||
RNA Seq Atlas | 540733 | ||||||||||||||